Problems and Solutions in Biological Sequence Analysis

Mark Borodovsky, Svetlana Ekisheva

346 pages, parution le 12/09/2006

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Résumé

This book is the first of its kind to provide a large collection of bioinformatics problems with accompanying solutions. Notably, the problem set includes all of the problems offered in Biological Sequence Analysis (BSA), by Durbin et al., widely adopted as a required text for bioinformatics courses at leading universities worldwide. Although many of the problems included in BSA as exercises for its readers have been repeatedly used for homework and tests, no detailed solutions for the problems were available. Bioinformatics instructors had therefore frequently expressed a need for fully worked solutions and a larger set of problems for use on courses. This book provides just that: following the same structure as BSA and significantly extending the set of workable problems, it will facilitate a better understanding of the contents of the chapters in BSA and will help its readers develop problem-solving skills that are vitally important for conducting successful research in the growing field of bioinformatics. All of the material has been class-tested by the authors at Georgia Tech, where the first ever M.Sc. degree program in Bioinformatics was held.

Sommaire

Preface
Introduction
Pairwise alignment
Markov chains and hidden Markov models
Pairwise alignment using HMMs
Profile HMMs for sequence families
Multiple sequence alignment methods
Building phylogenetic trees
Probabilistic approaches to phylogeny
Transformational grammars
RNA structure analysis
Background on probability

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Caractéristiques techniques

	PAPIER
Éditeur(s)	Cambridge University Press
Auteur(s)	Mark Borodovsky, Svetlana Ekisheva
Parution	12/09/2006
Nb. de pages	346
Format	17,5 x 24,5
Couverture	Broché
Poids	719g
Intérieur	Noir et Blanc
EAN13	9780521612302
ISBN13	978-0-521-61230-2