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Algorithms on strings, trees &sequences
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Algorithms on strings, trees &sequences

Algorithms on strings, trees &sequences

Computer Science and Computational Biology

Dan Gusfield

534 pages, parution le 27/09/2004

Résumé

Algorithms on text (strings) have long been studied in computer science, and computation on molecular sequence data (strings) is at the heart of computational molecular biology. Present and potential algorithms for string computation provide a significant intersection between computer science and molecular biology.

This book is a general, rigorous treatment of algorithms that operate on character strings and sequences. It covers a wide spectrum of string algorithms from classical computer science to modem molecular biology and, when possible, integrates those two fields.

In addition to explaining current algorithms, the book emphasizes fundamental ideas and techniques that are central in today's applications and should lead to new techniques, in the future. The book contains new approaches developed for complex material, simplifying methods that have been previously for the specialist alone. Biological problems are discussed in detail to explain the reasons that many biological questions have been productively cast as string problems.

The book is written for graduate or advanced undergraduate students in computer science, or computational biology, or bio-informatics. it can be used as a main text for courses on string algorithms, or for computer science oriented courses on computational biology and is aiso a reference for professionals. The book contains over 400 exercises to reinforce presented material, and to develop additional topics.

Sommaire

  • I. Exact String Matching : The Fundamental String Problem
    • Exact matching: fundamental preprocessing and first algorithms
    • Exact matching: classical comparison-based methods
    • Exact matching: a deeper look at classical methods
    • Semi-numerical string matching;
  • II. Suffix Trees And Their Uses
    • Introduction to suffix trees
    • Linear time construction of suffix trees
    • First applications of suffix trees
    • Constant time lowest common ancestor retrieval
    • More applications of suffix trees
  • III. Inexact Matching, Sequence Alignment, And Dynamic Programming
    • The importance of (sub)sequence comparison in molecular biology
    • Core string edits, alignments, and dynamic programming
    • Refining core string edits and alignments
    • Extending the core problems
    • Multiple string comparison : the Holy Grail
    • Sequence database and their uses: the motherlode
  • IV. Currents, Cousins And Cameos
    • Maps, mapping, sequencing and superstrings
    • Strings and evolutionary trees
    • Three short topics
    • Models of genome-level mutations
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Caractéristiques techniques

  PAPIER
Éditeur(s) Cambridge University Press
Auteur(s) Dan Gusfield
Parution 27/09/2004
Nb. de pages 534
Format 18,5 x 26
Couverture Relié
Poids 1107g
Intérieur Noir et Blanc
EAN13 9780521585194

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