Gene Genealogies, Variation and Evolution

A Primer in Coalescent Theory

Jotun Hein, Mikkel H. Schierup, Carsten Wiuf

276 pages, parution le 28/12/2004

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Résumé

Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia

Readership:
Graduate students and researchers in statistics, biosciences and medicine

L'auteur - Jotun Hein

Jotun Hein, Professor of Bioinformatics Department of Statistics, University of Oxford

L'auteur - Mikkel H. Schierup

Mikkel Schierup, Bioinformatics Research Center, University of Aarhus, Denmark

L'auteur - Carsten Wiuf

Carsten Wiuf, Bioinformatics Research Center, University of Aarhus, Denmark

Sommaire

Preface
The basic coalescent
From genealogies to sequences
Trees and topologies
Extensions to the basic coalescent
The coalescent with recombination
Getting parameters from data
LD Mapping and the coalescent
Human evolution
Appendix: Web based tools

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	PAPIER
Éditeur(s)	Oxford University Press
Auteur(s)	Jotun Hein, Mikkel H. Schierup, Carsten Wiuf
Parution	28/12/2004
Nb. de pages	276
Format	17 x 24,5
Couverture	Broché
Poids	607g
Intérieur	Noir et Blanc
EAN13	9780198529965
ISBN13	978-0-19-852996-5