Introduction to Stereochemistry

Kurt Mislow

194 pages, parution le 15/05/2003

Ajouter à une liste

Indisponible

Résumé

Molecular shape, form, and symmetry play a central role in organic chemistry, and this book presents a brief introduction to the conceptual basis of stereochemistry. The three-part text deals with structure and symmetry; stereoisomerism; and the separation and configuration of stereoisomers. The first section reviews molecular architecture, relating empirical bonding geometries to the hybridization of the central carbon atom. Students receive a nonrigorous treatment of symmetry elements and point groups, with particular focus on the presence or absence of reflection symmetry. The second section classifies stereoisomers according to symmetry properties and to the nature of their barriers; it also discusses the dependence of optical activity on structure and concludes with an examination of topological isomerism. The third and final section explores the conceptual basis of asymmetric syntheses and kinetic resolutions. Each of the major sections features a series of exercises that reinforce and extend the preceding material, and answers are provided.

Contents

Structure and Symmetry

Introduction
Bonding Geometries in Carbon Compounds
Bonding Orbitals in Carbon Compounds
Reflection Symmetry-Point Groups
Molecular Deformations and Strain Energies
Molecular Models
Exercises

Stereoisomerism

Classification of Structural Isomerism-Enantio-
meric and Diastereomeric Relationships
Optical Activity
Diastereomers and Racemic Forms
Torsional Stereoisomerism
Stereoisomerism Resulting from Asymmetric Atoms-Designation of Configuration at Asymmetric Atoms
Torsional Stereoisomerism in the Presence of Asymmetric Atoms
Macromolecules
Topological Isomerism
Exercises

Separation and Configuration of Stereoisomers

Separation of Enantiomers and Diastereomers
Optical Activation
Asymmetric Synthesis and Kinetic Resolution
Absolute Configuration
Configurational Correlations by Chemical Methods
Configurational Correlations by Physical Methods
Exercises

Caractéristiques techniques

	PAPIER
Éditeur(s)	Dover
Auteur(s)	Kurt Mislow
Parution	15/05/2003
Nb. de pages	194
Format	13,5 x 21,5
Couverture	Broché
Poids	220g
Intérieur	Noir et Blanc
EAN13	9780486425306
ISBN13	978-0-486-42530-6