Making Mice

Standardizing Animals for American Biomedical Research, 1900-1955

Karen Rader

299 pages, parution le 22/04/2004

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Résumé

Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research.

Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice.

This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.

Sommaire

Mice, medicine and genetics: from pet rodents to research materials (1900-21)
Experiment and change: institutionalizing inbred mice (1922-30)
Mice for sale: commodifying research animals (1930-33)
A new deal for mice: biomedicine as big science (19303-40)
RxMouse: JAX Mice in cancer research (1938-55)
Mouse Genetics as public policy: radiation risk in cold war America (1946-56)
Epilogue: animals and the nex biology: oncomouse and beyond

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Caractéristiques techniques

	PAPIER
Éditeur(s)	Princeton University Press
Auteur(s)	Karen Rader
Parution	22/04/2004
Nb. de pages	299
Format	16 x 24
Couverture	Relié
Poids	600g
Intérieur	Noir et Blanc
EAN13	9780691016368
ISBN13	978-0-691-01636-8