Principles of Genetics

New to this edition

• Over 100 pieces of line art are either new or revised, and all of the line art and tables from the text will be available for downloading on the text-specific website.
• Chapter reorganization. The molecular genetics coverage (Chapters 9-17) has been reorganized to include such things as numerous repair DNA polymerases and their functioning, base-flipping, TRAP control of attenuation, and chromatosomes.
• --Chapter 12--DNA: Its Mutation, Repair and Recombination has been moved earlier to the text to follow material on transcription and translation.
• --Chapter 13 — Genomics, Biotechnology, and Recombinant DNA has been updated to place more emphasis on modern-day genomics (The Human Genome Project, bioinformatics, proteomics, and the latest techniques in creating cDNA and knockout mice).
• --Chapter 16 — Gene Expression: Control in Eukaryotes has been completely reorganized and rewritten to emphasize signal transduction, specific transcription factors, methylation, and chromatin remodeling in control of gene expression with specific sections on Drosophila and plant development, cancer, and immunogenetics.
• Customize this book through Primis Online! This title will be part of the Primis Online Database: www.mhhe.com/primis/online. You can customize this book to meet your exact needs and mix and match with other items on Primis Online--allowing you maximum choice and flexibility. You can also choose between two delivery formats: custom printed books (in black and white) or custom eBooks (in color).

• Tamarin divides his chapters into three units (classical, population, and molecular), making it easy for professors to customize their courses to the way they want to teach it and making it easy for the student to differentiate the three areas.
• A large quantity of end-of-chapter problems (including critical thinking questions) are organized under major chapter headings to help students learn in smaller segments and reduce confusion with already challenging subject matter.
• Tamarin does an excellent job of distinguishing Eukaryotic from Prokaryotic processes by discussing the same topic but in separate chapters, making it less confusing for the students (i.e. Ch 6--Linkage Mapping in Eukaryotes; Ch 7--Linkage Mapping in Prokaryotes and Bacterial Viruses).
• Throughout this text, the implications for human health and welfare of the research conducted in universities and research laboratories around the world are pointed out.

I Genetics and the Scientific Method

1 Introduction

II Mendelism and the Chromosomal Theory

2 Mendel's Principles

3 Mitosis and Meiosis

4 Probability and Statistics

5 Sex Determination, Sex Linkage, and Pedigree Analysis

6 Linkage and Mapping in Eukaryotes

7 Linkage and Mapping in Prokaryotes and Bacterial Viruses

8 Cytogenetics

III Molecular Genetics

9 Chemistry of the Gene

10 Gene Expression: Transcription

11 Gene Expression: Translation

12 DNA: Its Mutation, Repair, and Recombination

13 Genomics, Biotechnology, and Recombinant DNA

14 Gene Expression: Control in Prokaryotes and Phages

15 The Eukaryotic Chromosome

16 Gene Expression: Control in Eukaryotes

17 Non-Mendelian Inheritance

IV Quantitative and Evolutionary Genetics

18 Quantitative Inheritance

19 Population Genetics: The Hardy-Weinberg Equilibrium and Mating Systems

20 Population Genetics: Processes That Change Allelic Frequencies

Appendix A Brief Answers to Selected Exercises, Problems, and Critical Thinking Questions

Appendix B Suggestions for Further Reading