Statistics for Microarrays

Design, Analysis and Inference

John McClure, Ernst Wit

265 pages, parution le 18/08/2004

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Résumé

Interest in microarrays has increased considerably in the last ten years. This increase in the use of microarray technology has led to the need for good standards of microarray experimental notation, data representation, and the introduction of standard experimental controls, as well as standard data normalization and analysis techniques. Statistics for Microarrays: Design, Analysis and Inference is the first book that presents a coherent and systematic overview of statistical methods in all stages in the process of analysing microarray data - from getting good data to obtaining meaningful results.

Provides an overview of statistics for microarrays, including experimental design, data preparation, image analysis, normalization, quality control, and statistical inference.
Features many examples throughout using real data from microarray experiments.
Computational techniques are integrated into the text.
Takes a very practical approach, suitable for statistically-minded biologists.
Supported by a Website featuring colour images, software, and data sets.

Primarily aimed at statistically-minded biologists, bioinformaticians, biostatisticians, and computer scientists working with microarray data, the book is also suitable for postgraduate students of bioinformatics.

Sommaire

Preliminaries
Getting Good Data
- Set-up of a Microarray Experiment
- Statistical Design of Microarrays
- Normalization
- Quality Assessment
- Microarray Myths: Data
Getting Good Answers
- Microarray Discoveries
- Differential Expression
- Predicting Outcomes with Gene Expression Profiles
- Microarray Myths: Inference

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Caractéristiques techniques

	PAPIER
Éditeur(s)	Wiley
Auteur(s)	John McClure, Ernst Wit
Parution	18/08/2004
Nb. de pages	265
Format	15,5 x 23,5
Couverture	Relié
Poids	530g
Intérieur	Noir et Blanc
EAN13	9780470849934
ISBN13	978-0-470-84993-4