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Protein Actions

Protein Actions

Ken dill (author)|robert l. jernigan (author)|hue-sun chan (author)|ivet bahar (author)

336 pages, parution le 22/03/2017

Résumé

1. Proteins are Polymers that Fold into Specific Structures
2. Proteins Perform Cellular Functions
3. Proteins Have Stable Equilibrium Conformations
4. Protein Binding Leads to Biological Actions
5. Folding and Aggregation Are Cooperative Transitions
6. The Principles of Protein Folding Kinetics
7. Proteins Evolve
8. Bioinformatics: Insights from Protein Sequences
9. Protein Geometries and Energetics
10. Molecular Simulations and Conformational Sampling
11. Predicting Protein Structures from Sequences
12. Biological Actions Arise from Protein Motions
13. Molecular Modeling for Drug Discovery

Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers.

The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.

1st editionIllustrationsQD431Proteins.1New York (State)New YorkIvet Bahar, Robert L. Jernigan, Ken A. Dill.

Caractéristiques techniques

  PAPIER
Éditeur(s) Taylor&francis
Auteur(s) Ken dill (author)|robert l. jernigan (author)|hue-sun chan (author)|ivet bahar (author)
Parution 22/03/2017
Nb. de pages 336
Format 278 x 216
Poids 910g
EAN13 9780815341772

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