Human Molecular Biology

An introduction to the Molecular Basis of Health and Disease

Richard J. Epstein

654 pages, parution le 07/11/2002

Ajouter à une liste

Indisponible

Résumé

Human Molecular Biology is an introduction to the molecular basis of health and disease for the new generation of life scientists and medical students. By integrating cutting-edge molecular genetics and biochemistry with the latest clinical information, the book weaves a pattern which unifies biology with syndromes, genetic pathways with developmental phenotypes, and protein function with drug action. From the origins of life to the present day, a narrative is traced through the workings of genomes, cells and organ systems, culminating in linking of laboratory technologies to future research horizons. Lavishly illustrated throughout with two-colour diagrams and full colour clinical pictures, this text brings the complexities and breadth of human molecular biology clearly to life.

This seamless account breaks through the boundaries between molecular biology and medicine, and leads the reader on to a new dimension where the biological basis of health and disease is inescapably molecular.

Contents

Part I. From Molecular biology to human genetics

Biomolecular evolution
Chromatin and chromosomes
Gene expression
Gene expression
RNA processing and translation
Protein structure and function

Part II. From Molecular Genetics to Human Biochemistry

Nutrition and energy
Membranes and channels
Cell-surface receptors and antigene redognition
Cytoskeletal and molecular motors

Part III. From Molecular Biochemistry to Human Cell Biology

Signal transduction
Bioactive lipids and inflammatory cytokines
Hormones and growth factors
Hemopoietins, angiogenins and vasoactive mediators
Cell cycle control, apoptosis and ageing

Part IV. From Molecular Cell Biology to Human Physiology

Development
Metabolism
Blood
Immunity
Neurobiology

Part V. From Molecular Physiology to Human Molecular Biology

Genetic experimental systems
Gene and protein analysis
Genetic engineering, gene mapping and gene testing
Gene knockouts, transgenics, and cloned
Gene therapy and recombinant DNA technology

Caractéristiques techniques

	PAPIER
Éditeur(s)	Cambridge University Press
Auteur(s)	Richard J. Epstein
Parution	07/11/2002
Nb. de pages	654
Format	22 x 27,5
Couverture	Broché
Poids	2018g
Intérieur	Quadri
EAN13	9780521644815
ISBN13	978-0-521-64481-5