Genome Mapping and Sequencing

Ian Dunham

470 pages, parution le 02/03/2004

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Résumé

Acknowledged experts in the field of DNA sequencing and mapping describe in detail the latest innovations in this vital area of science. The newest technology and procedures in areas such as radiation hybrid mapping, construction of libraries, YACs, FISH, assembly of physical maps, shotgun sequencing and specialized sequencing techniques are all fully covered. There is a particular emphasis on the whole chromosome approach to mapping and sequencing. In addition several chapters cover genomic sequencing software and sequence databases.
Eminent international scientists describe the technology necessary to map and sequence the entire genome in a holistic manner and the high throughput and large-scale experimental methodologies currently available. An essential volume for everyone involved in DNA sequencing and mapping.

Key Features:

Completely up-to-date
Expert authors
Illustrated throughout
Comprehensive reference sections
Describes theory and practise
Focus on new technology and software

L'auteur - Ian Dunham

The Sanger Centre, Cambridge

Sommaire

Parameters of a new genome
Hugues Roest Crollius.
Radiation hybrid mapping - A whole chromosome approach
Panos Deloukas.
Construction of large-insert bacterial clone libraries
Jeffrey Garnes, Marguerite Ciancio and Andreas Gnirke.
The use of YACs in mapping and sequencing
Michael A. Quail and Alan Coulson.
Fluorescence In Situ Hybridisation, Flow-sorting and Related Technologies
Susan Gribble.
Assembling Physical Maps and Sequence Clone Selection
Andrew J. Mungall and Sean J. Humphray.
FPC: A Software Package for Physical Maps
Fred Engler and Cari Soderlund.
Mapping Pericentromeric Regions
Devin P. Locke, Julie E. Horvath and Evan E. Eichler.
Cloning, mapping, and sequencing telomeres
Harold Riethman.
Shotgun Sequencing
M.C. Jones and S.K. Sims.
Finishing Genomic Sequence and Dealing with Problem Sequences
Adrienne R. Hunt, David L. Willey and Michael A. Quail.
Software for Genomic Sequencing
Michael C. Wendl, Asif T. Chinwalla, and LaDeana W. Hillier.
Annotating Mammalian Genome Sequence
John E. Collins and David M. Beare.
Sequence Databases
Gregory D. Schuler
Index

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Caractéristiques techniques

	PAPIER
Éditeur(s)	Horizon press
Auteur(s)	Ian Dunham
Parution	02/03/2004
Nb. de pages	470
Format	16 x 24
Couverture	Broché
Poids	1020g
Intérieur	Noir et Blanc
EAN13	9781898486503