Biochemistry

Jeremy Berg, John L. Tymoczko, Lubert Stryer

1050 pages, parution le 22/03/2002 (5^eme édition)

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Résumé

With the addition of two new co-authors, Biochemistry takes a new direction, as it becomes the first text to fully reflect the revolution that has taken place in biomedical science in the past ten years, culminating in the human genome project. A key focus of the new edition is the unifying features of protein structure and function that have been revealed by the incredible progress in gene sequencing. Such features are highlighted in a way that will help students master the complex and intricate subject matter.

As you know, the development of drugs is one of the most important interfaces between biochemistry and medicine--knowledge of biochemical pathways is key in the development of new drugs. Moreover, the pharmaceutical industry has become a center of controversy of late, and an understanding of drug development is important for understanding health policy and economic issues.

In planning the upcoming Sixth Edition of Biochemistry (publishing in 2006), our authors felt that it was very important to include a chapter on drug development in the book. They wanted students and instructors to have access to this new material as soon as possible, so we have decided to publish this new chapter as a supplement to the Fifth Edition. This drug development chapter explores the science of pharmacology by examining a number of case histories that illustrate drug development-including many of its concepts, methods, and challenges.

L'auteur - Jeremy Berg

Ecole de médecine de l'Université Johns Hopkins.

L'auteur - John L. Tymoczko

Collège Carleton.

L'auteur - Lubert Stryer

Université de Stanford.

Sommaire

Molecular design of life
- 1. Prelude
- 2. Biochemical Evolution-NEW
- 3. Protein Structure and Function
- 4. Exploring Proteins
- 5. RNA and DNA: The Flow of Genetic Information
- 6. Exploring Genes
- 7. Exploring Evolution-NEW
- 8. Enzymes: Basic Concepts and Kinetics
- 9. Catalytic Strategies
- 10. Regulatory Strategies
- 11. Carbohydrates
- 12. Lipids and Cell Membranes
- 13. Membrane Channels and Pumps
Generating and storing energy
- 14. Metabolism: Basic Concepts and Design
- 15. Signal Transduction
- 16. Glycolysis and Gluconeogenesis
- 17. Pentose Phosphate Pathway and the Calvin Cycle
- 18. Citric Acid Cycle
- 19. Oxidative Phosphorylation
- 20. Photosynthesis
- 21. Glycogen Metabolism
- 22. Fatty Acid Metabolism
- 23. Protein Turnover: Amino Acid Degradation and the Urea Cycle
Synthesizing the molecules of life
- 24. Biosynthesis of Amino Acids
- 25. Biosynthesis of Nucleotides
- 26. Biosynthesis of Lipids and Related Molecules
- 27. DNA Replication and Repair
- 28. RNA Synthesis and Splicing
- 29. Protein Synthesis
- 30. Integration of Metabolism
Responding to environmental changes
- 31. Control of Gene Expression
- 32. Sensory Systems-NEW
- 33. The Immune System
- 34. Molecular Motors

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Caractéristiques techniques

	PAPIER
Éditeur(s)	W.H. Freeman and Company
Auteur(s)	Jeremy Berg, John L. Tymoczko, Lubert Stryer
Parution	22/03/2002
Édition	5^eme édition
Nb. de pages	1050
Format	22,5 x 28
Couverture	Relié
Poids	2450g
Intérieur	Quadri
EAN13	9780716746843